exceptions.AttributeError, interfaces down or host unreachable

Greetings, I'm using offlineimap 6.3.4 on F16 3.1.0-7. My python is 
2.7.3. Also, to access the BigC account (noted in the error below) I'm 
using something called davmail-3.9.6-1. Davmail basically acts as an 
imap to exchange proxy.

I've been able to do clean runs on these accounts in the past. But 
within the past week I repeatedly get these errors. It's difficult for 
me to associate which account --or clearly determine what the issue is.

Any suggestions?

[root <at> fuzzy ~]# offlineimap

WARNING: UID validity problem for folder .mailboxlist (repo 
RemoteMyStuff) (saved 1343439460; got 1343596775); skipping it

WARNING: ERROR attempting to copy message 12057 for account 
BigC:Traceback (most recent call last):

   File "/usr/lib/python2.7/site-packages/offlineimap/folder/Base.py", 
line 250, in copymessageto
     message = self.getmessage(uid)
   File "/usr/lib/python2.7/site-packages/offlineimap/folder/IMAP.py", 
line 205, in getmessage
     res_type, data = imapobj.uid('fetch', str(uid), '(BODY.PEEK[])')
   File "/usr/lib/python2.7/site-packages/offlineimap/imaplib2.py", line 
1110, in uid
     return self._simple_command('UID', command, *args, **kw)
   File "/usr/lib/python2.7/site-packages/offlineimap/imaplib2.py", line